![]() "As a result, the most common source for heparin is pig intestinal tissue, with the vast majority of the world's supply coming from China."Ĭhina is responsible for 80% of the global crude heparin supply and 50% of the world's pig population. "There was concern about using medications derived from cows, so there was a big push to move towards heparin derived from pigs," Dr. Historically, cow lung tissue was used until a bovine spongiform encephalopathy (mad cow disease) outbreak in the 1990s. Manufacturers source heparin from animal tissue. Repeating History: Examining the Heparin Shortage Due to Swine Flu Surgeons also use protamine in the OR to control heparin's effects after cardiac surgery ![]() When patients have acute bleeding problems, clinicians can give them protamine to "turn off" the heparin.
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